From Zero to Breakthrough

A podcast about Founders, Innovators, Researchers and Disrupters shaping Australia’s future.

Why This Podcast Exists

After nearly a decade in investment banking, working closely with founders and raising millions for startups, one thing became clear: success almost never follows a linear path. The most interesting lessons live in the detours, the mistakes, and the turning points. On-Ramp is a place to unpack those moments, through honest conversations with people building, backing, and shaping what’s next.

Featured Conversations

A curated look at recent episodes and standout moments. Short previews so you know what you’re getting before you commit your time.

Ex-Mastercard AI Expert Explains What’s Coming Next | Ep12

Artificial intelligence has transformed how we write, search and work.

But what if the next AI revolution isn’t about text at all?

In this episode of On-Ramp, I sit down with Finbar O’Hanlon, AI specialist, former Mastercard executive, and Chief Commercial Officer at ION (ASX:IOV), to explore why video is emerging as the next frontier for artificial intelligence.

As AI agents become more capable and enterprises generate enormous volumes of video content, a new challenge has emerged: how do we make video searchable, programmable and useful for AI?

We discuss:

• Why ChatGPT is only the beginning of the AI revolution

• Why video is one of AI’s biggest untapped opportunities

• How AI will transform media, education and enterprise

• The rise of AI agents and personalised content

• Why most businesses still struggle to adopt AI effectively

• How ION is building infrastructure for the next generation of video

• The future of search, streaming and digital experiences

Whether you’re an investor, founder, technologist or simply curious about where AI is heading next, this conversation offers a fascinating look at one of the most overlooked trends shaping the next decade.

If you enjoyed this episode, please like, subscribe and share it with someone interested in AI, technology and innovation.

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🎙️ About On-Ramp

On-Ramp is a long-form podcast exploring the ideas, technologies and people shaping the future of business, investing and innovation.

New episodes every fortnight.

#AI #ArtificialIntelligence #VideoAI #Technology #Innovation #MachineLearning #GenerativeAI #FutureOfWork #Startups #DeepTech #ASX #ION #Podcast

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Did We Get Psychedelics Wrong For 50 Years? I asked an expert | Ep 11

Psychedelics have gone from counterculture to cutting-edge medicine.

In this episode of On-Ramp, I sit down with neuroscientist and psychedelic medicine researcher Dr Berra Yazar-Klosinski to explore why compounds like MDMA, psilocybin and ketamine are being re-evaluated by scientists, clinicians and regulators around the world.

Once dismissed as dangerous recreational drugs, these compounds are now showing promise in treating conditions such as PTSD, treatment-resistant depression and anxiety. We unpack the science behind the psychedelic renaissance, why these therapies were prohibited for decades, and what modern neuroscience is revealing about the brain’s remarkable capacity to heal.

We also dive into Dr Berra’s latest research on the epigenetic effects of ketamine and MDMA, exploring how these emerging psychoplastogens may promote lasting changes in the brain beyond the immediate therapeutic experience.

In this episode, we discuss:

• Why psychedelics were banned and why attitudes are changing
• The science behind psychedelic-assisted therapy
• How psychedelics may promote neuroplasticity
• The role of consciousness and interoception in mental health
• The latest clinical evidence for PTSD and depression
• Australia’s leadership in psychedelic medicine
• What the future holds for one of the most exciting frontiers in healthcare

Whether you’re interested in neuroscience, mental health, biotechnology or the future of medicine, this conversation offers a balanced, evidence-based look at one of the fastest-evolving fields in healthcare.

If you enjoyed this episode, please like, subscribe and share it with someone who’d find it interesting.

#Psychedelics #MentalHealth #Neuroscience #MDMA #Psilocybin #Ketamine #Psychiatry #Healthcare #Innovation #OnRampPodcast

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The Hidden Funding Aussie Startups Miss: Explained by a Grants Expert | Ep 7

Most founders overlook non-dilutive funding, or don’t use it effectively.

In this episode, I sit down with Stuart Haines from Haines Consulting Group to break down the major grant programs available in Australia right now, how to actually structure them into your funding strategy, and where most startups go wrong when applying.

We also cover:

* The biggest grant opportunities founders should be looking at
* How to think about grants vs equity funding
* Common mistakes that kill applications
* What “grant-ready” actually looks like
* Stuart’s journey building a business in this space

If you’re building in Australia, this is a practical guide to using grants as a tool, not a crutch.

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What People Are Saying

“At first I thought it was just another interview-style podcast, but the questions are sharper and the conversations breathe. It feels less like content and more like sitting in on a real discussion where no one is rushing to impress anyone.”

“Finally a podcast where people finish a thought instead of chasing clips.”

“If you’re tired of podcasts that sound like rehearsed talking points, this feels like a reset. The conversations go off-script in a good way, and you can tell the hosts actually listen instead of waiting for their turn to talk. Some episodes stick with you longer than you expect.”

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